Cardiff full back Liam Williams has been ruled out of Wales' Guinness Six Nations finale against France on Saturday.
The British and Irish Lion crossed for his second try of the campaign as Warren Gatland's men secured their first victory in Rome last week.
However, the Blue and Blacks full back departed with a shoulder injury in the second half, after an aerial collision, and will undergo further assessment.
Ospreys duo Scott Baldwin (pec) and Keiran Williams (groin) have also been ruled out, with club team-mate Sam Parry called into the national squad.
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